A collection of studies on preterm infants and the effects of human milk fortifiers (HMF) and probiotics on their growth and nutrient intake.
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A collection of studies on preterm infants and the effects of human milk fortifiers (HMF) and probiotics on their growth and nutrient intake.
An interventional study compared body composition and growth outcomes of very low-birth-weight infants fed targeted protein-fortified human milk (HM) with those fed standard fortified HM.
Parat S, et al. Nutrients. 2020:12(4):1156. https://doi.org/10.3390/nu12041156
A study which compared and quantified effects on premature infants being fed Acidified Liquid HMF (ALHMF) versus those receiving powdered HMF (PHMF).
Thoene, M., Hanson, C., Lyden, E., Dugick, L., Ruybal, L., & Anderson-Berry, A. Comparison of the effect of two human milk fortifiers on clinical outcomes in premature infants. Nutrients. 2014; 6(1), 261–275. https://doi.org/10.3390/nu6010261
This ESPGHAN probiotic meta-analysis paper identifies strains with high efficacy and addresses safety issues of probiotic supplementation to preterm infants, who have reduced immunological capacities and occasional indwelling catheters.
van den Akker, C., van Goudoever, J. B., Shamir, R., Domellöf, M., Embleton, N. D., Hojsak, I., Lapillonne, A., Mihatsch, W. A., Berni Canani, R., Bronsky, J., Campoy, C., Fewtrell, M. S., Fidler Mis, N., Guarino, A., Hulst, J. M., Indrio, F., Kolaček, S., Orel, R., Vandenplas, Y., Weizman, Z., Szajewska, H. (2020). Probiotics and Preterm Infants: A Position Paper by the European Society for Paediatric Gastroenterology Hepatology and Nutrition Committee on Nutrition and the European Society for Paediatric Gastroenterology Hepatology and Nutrition Working Group for Probiotics and Prebiotics. Journal of Pediatric Gastroenterology and Nutrition, 70(5), 664–680. https://doi.org/10.1097/MPG.0000000000002655
A controlled study with the goal of comparing growth, feeding tolerance, and clinical and biochemical evaluations in human milk-fed preterm infants who received either an acidified or nonacidified liquid human milk fortifier.
Schanler, R. J., Groh-Wargo, S. L., Barrett-Reis, B., White, R. D., Ahmad, K. A., Oliver, J., Baggs, G., Williams, L., & Adamkin, D. (2018). Improved Outcomes in Preterm Infants Fed a Nonacidified Liquid Human Milk Fortifier: A Prospective Randomized Clinical Trial. The Journal of Pediatrics, 202, 31–37.e2. https://doi.org/10.1016/j.jpeds.2018.07.005
This study was a comparison of growth and tolerance in premature infants fed either standard powdered human milk fortifier (HMF) or a newly formulated concentrated liquid that contained extensively hydrolyzed protein.
Kim, J. H., Chan, G., Schanler, R., Groh-Wargo, S., Bloom, B., Dimmit, R., Williams, L., Baggs, G., & Barrett-Reis, B. (2015). Growth and Tolerance of Preterm Infants Fed a New Extensively Hydrolyzed Liquid Human Milk Fortifier. Journal of Pediatric Gastroenterology and Nutrition, 61(6), 665–671. https://doi.org/10.1097/MPG.0000000000001010
A double-blind study evaluating the growth of preterm infants fed nutrient-enriched or term formula after hospital discharge.
Carver, J. D., Wu, P. Y., Hall, R. T., Ziegler, E. E., Sosa, R., Jacobs, J., Baggs, G., Auestad, N., & Lloyd, B. (2001). Growth of preterm infants fed nutrient-enriched or term formula after hospital discharge. Pediatrics, 107(4), 683–689. https://doi.org/10.1542/peds.107.4.683
This study evaluates growth and body composition in premature infants who were fed formulas that contain long-chain polyunsaturated fatty acids.
Groh-Wargo, S., Jacobs, J., Auestad, N., O'Connor, D. L., Moore, J. J., & Lerner, E. (2005). Body composition in preterm infants who are fed long-chain polyunsaturated fatty acids: a prospective, randomized, controlled trial. Pediatric Research, 57(5 Pt 1), 712–718. https://doi.org/10.1203/01.PDR.0000156509.29310.55
A randomized trial which assessed growth and development in premature infants fed formulas with oils containing the long-chain polyunsaturated fatty acids.
O'Connor, D. L., Hall, R., Adamkin, D., Auestad, N., Castillo, M., Connor, W. E., Connor, S. L., Fitzgerald, K., Groh-Wargo, S., Hartmann, E. E., Jacobs, J., Janowsky, J., Lucas, A., Margeson, D., Mena, P., Neuringer, M., Nesin, M., Singer, L., Stephenson, T., Szabo, J., … Ross Preterm Lipid Study (2001). Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial. Pediatrics, 108(2), 359–371. https://doi.org/10.1542/peds.108.2.359
A prospective comparison of Enfamil and Similac liquid human milk fortifier on growth and metabolic outcomes in premature infants.
Kumar, N., Monga, R., Sampath, V., & Ehrhart, B. (2017). Prospective Comparison of Enfamil and Similac Liquid Human Milk Fortifier on Clinical Outcomes in Premature Infants. American Journal of Perinatology, 34(14), 1411–1416. https://doi.org/10.1055/s-0037-1603940
A recommended list of indicators for identification and documentation of malnutrition in preterm infants and neonates.
Goldberg, D. L., Becker, P. J., Brigham, K., Carlson, S., Fleck, L., Gollins, L., Sandrock, M., Fullmer, M., & Van Poots, H. A. (2018). Identifying Malnutrition in Preterm and Neonatal Populations: Recommended Indicators. Journal of the Academy of Nutrition and Dietetics, 118(9), 1571–1582. https://doi.org/10.1016/j.jand.2017.10.006
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