Studies analyzing challenges surrounding preterm infant nutrition, growth, and development.
Studies analyzing challenges surrounding preterm infant nutrition, growth, and development.
Find guidelines developed for preparing families for NICU discharge and the transition to at-home care. These recommendations are specific and actionable, while being general enough to adapt to the needs of your practice.
Smith VC, Love K, Goyer E. J Perinatol. 2022;42(Suppl 1):7-21. doi:10.1038/s41372-022-01313-9
This review discusses opportunities to provide support to families with preterm infants following NICU discharge. Intervention measures, such as family-focused communication, can help to provide parents with continued education, promote emotional support, and reduce unplanned hospital visits.
Griffith T, Singh A, Naber M, et al. J Pediatr Nurs. 2022;67:e135-e149. doi:10.1016/j.pedn.2022.08.014
Explore a review summarizing evidence regarding preterm infant enteral nutrition and early postnatal growth.
Wiechers C, Bernhard W, Goelz R, Poets CF, Franz AR. Int J Environ Res Public Health. 2021;18(14):7544. Published 2021 Jul 15. doi:10.3390/ijerph18147544
This review examined and reanalyzed existing evidence to clarify the ways this body of clinical research may have a positive impact on the post-discharge nutrition approach to preterm infants.
Lucas A, Sherman J, Fewtrell M. Neoreviews. 2022;23(8):e541-e557. doi:10.1542/neo.23-8-e541
This article reviews the history of acidified feedings in infants and contemporary research on the use of acidified human milk fortifiers, its effects on preterm infants, and the underlying physiological mechanisms of action.
Barrett-Reis B, Shakeel F, Dennis L, Baggs G, Masor ML. Am J Perinatol. 2023;40(2):141-148. doi:10.1055/s-0042-1749166
This study examines recent findings on the neonatal gut microbiome and discusses their implications for understanding this driver of the maturation of the immune system and immunity against infections.
Sanidad KZ, Zeng MY. Curr Opin Microbiol. 2020;56:30-37. doi:10.1016/j.mib.2020.05.011
Read a study that explored feeding practices versus feeding guideline adherence for nutritionally vulnerable VLBW infants. This study followed post-discharge feeding practices for those born VLBW to see if they aligned with current recommendations.
Francis J, Unger S, Bando N, et al. J Pediatr Gastroenterol Nutr. 2018;67(3):401-408. doi:10.1097/MPG.0000000000002041
Read a study which assessed the effects of enteral vitamin D supplementation compared with no vitamin D supplementation in human milk-fed preterm or LBW infants.
Kumar M, Shaikh S, Sinha B, et al. Pediatrics. 2022;150(Suppl 1):e2022057092K. doi:10.1542/peds.2022-057092K
Review the clinical study that showed achievable catch-up growth in VPI when transitional formula complements human milk feeding.
Fernandes AI, Gollins LA, Hagan JL, Hair AB. J Perinatol. 2022. doi: 10.1038/s41372-022-01510-6
Infants in the study received initial feedings of donor breast milk, maternal breast milk, or donor breast milk with protein enrichment; followed by multi-nutrient-fortified human milk. Initial protein enrichment of donor breast milk appeared safe for stable very low-birth-weight infants.
Fu TT, Kaplan HC, Fields T, Folger AT, Gordon K, Poindexter BB. Nutrients. 2021;13(8):2869. doi:10.3390/nu13082869
An interventional study compared body composition and growth outcomes of very low-birth-weight infants fed targeted protein-fortified human milk (HM) with those fed standard fortified HM.
Parat S, Raza P, Kamleh M, Super D, Groh-Wargo S. Nutrients. 2020;12(4):1156. doi:10.3390/nu12041156
A study which compared and quantified effects of feeding acidified liquid HMF (ALHMF) versus powder HMF (PHMF) in a premature infant population.
Thoene M, Hanson C, Lyden E, Dugick L, Ruybal L, & Anderson-Berry A. Nutrients. 2014;6(1):261–275. https://doi.org/10.3390/nu6010261
This ESPGHAN probiotic meta-analysis paper identified strains with high efficacy and addressed safety issues of probiotic supplementation to preterm infants, who have reduced immunological capacities and occasional indwelling catheters.
van den Akker C, van Goudoever JB, Shamir R, et al. J Pediatr Gastroenterol Nutr. 2020;70(5):664-680. doi:10.1097/MPG.0000000000002655
A randomized, controlled study that compared growth, feeding intolerance, and clinical and biochemical evaluations in human milk-fed preterm infants who received either an acidified or nonacidified liquid human milk fortifier.
Schanler RJ, Groh-Wargo SL, Barrett-Reis B, et al. J Pediatr. 2018;202:31-37.e2. doi:10.1016/j.jpeds.2018.07.005
This randomized, controlled study compared growth and tolerance in premature infants fed human milk with either standard powdered human milk fortifier (HMF) or a newly formulated concentrated liquid HMF.
Kim JH, Chan G, Schanler R, et al. [Published correction appears in J Pediatr Gastroenterol Nutr. 2016 Jan;62(1):188-9]. J Pediatr Gastroenterol Nutr. 2015;61(6):665-671. doi:10.1097/MPG.0000000000001010
A double-blind study which evaluated the growth of preterm infants fed nutrient-enriched or term formula after hospital discharge.
Carver JD, Wu PY, Hall RT, et al. Pediatrics. 2001;107(4):683-689. doi:10.1542/peds.107.4.683
This study evaluated growth and body composition in premature infants who were fed formulas that contain long-chain polyunsaturated fatty acids.
Groh-Wargo S, Jacobs J, Auestad N, O'Connor DL, Moore JJ, & Lerner E. Pediatr Res. 2005;57(5 Pt 1):712–718. https://doi.org/10.1203/01.PDR.0000156509.29310.55
This study investigated impacts of early postnatal macronutrient intakes on growth and body composition of preterm infants within the first 6 months.
Han J, Zhang L, Li S, et al. Eur J Clin Nutr. 2022;76(1):103-110. doi:10.1038/s41430-021-00901-w
A randomized trial which assessed growth and development in premature infants fed formulas with oils containing long-chain polyunsaturated fatty acids.
O'Connor DL, Hall R, Adamkin D, et al. Pediatrics. 2001;108(2):359-371. doi:10.1542/peds.108.2.359
A prospective comparison of Enfamil and Similac liquid human milk fortifier on growth and metabolic outcomes in premature infants.
Kumar N, Monga R, Sampath V, & Ehrhart B. Am J Perinat. 2017;34(14), 1411–1416. https://doi.org/10.1055/s-0037-1603940
A recommended list of indicators for identification and documentation of malnutrition in preterm infants and neonates.
Goldberg DL, Becker PJ, Brigham K, et al. J Acad Nutr Diet. 2018;118(9):1571-1582. doi:10.1016/j.jand.2017.10.006
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