Individualized Nutrition for Customizable Liquid Nutrition Solutions

The Similac® Liqui-Mix® System for Easy Feeding Preparation

Premature Infant Fortifiers and Formulas

#1 Brand Fed In NICU Logo #1 Brand Fed In NICU Logo

Nutritional products specifically designed for preterm infants

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 50+ Years of Research 
 100+ Scientific Publications
Special Care Ready to Feed 2 FL OZ bottles, Liquid Protein Fortifier 2 FL OZ bottle, HMO Hydrolyzed Protein Fortifer Special Care Ready to Feed 2 FL OZ bottles, Liquid Protein Fortifier 2 FL OZ bottle, HMO Hydrolyzed Protein Fortifer
Extensive product line with flexible solutions to meet the unique nutrient needs of preterm infants:
Special Care Ready to Feed 2 FL OZ bottles group products Special Care Ready to Feed 2 FL OZ bottles group products

Similac® Special Care®

Iron-fortified feedings to help

support low-birth-weight and

premature infants and has our

unique blend of DHA, lutein,

and vitamin E for brain &

eye development

Liquid Mix System graphic Liquid Mix System graphic

All Similac Special Care

Premature Infant Formulas

can be used in the

Liqui-Mix System

Liquid protein fortifier bottle Liquid protein fortifier bottle

Liquid Protein Fortifier

The first & only

commercially sterile,

extensively hydrolyzed liquid

protein fortifier designed

for easy digestion and

individualized protein level

optimization

Use with human milk or

formula. Designed to be

mixed with human milk,

fortified human milk, or

formula feedings

HMF Extensively Hydrolyzed Protein Package HMF Extensively Hydrolyzed Protein Package

Similac® HMF HP CL

The only liquid HMF

with extensively hydrolyzed

protein and published clinical

studies demonstrating

excellent tolerance and

improved weight gain

Clinically proven growth

 and tolerance supported

 in 5 clinical studies

These formulations are specially designed to meet the unique nutritional requirements of most preterm infants in the NICU and can be fed with confidence.

SIMILAC LIQUI-MIX SYSTEM

The Similac Liqui-Mix System is a customizable, all-liquid feeding solution that delivers a high-calorie, nutrient-dense feeding to your NICU patients.

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Customizable

Flexible mixing allows you to prepare individualized feedings to meet the unique nutrition needs of each patient.

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Commercially Sterile

Premature infants are often immunocompromised and may be at high risk for developing infections. Powdered formulas are not commercially sterile.

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All-Liquid

Reconstituted powder infant formulas have potential for microbial growth and mixing errors.

The Academy of Nutrition and Dietetics and the CDC* recommend that powdered infant formulas should not be used in the NICU unless there is no nutritionally appropriate alternative available.

* Centers for Disease Control and Prevention.

FLEXIBLE MIXING SOLUTIONS

The Similac Liqui-Mix System gives you the ability to create individualized feedings to meet the unique nutrient needs of preterm infants.

Example recipes for various formula concentrations using the Liqui-Mix System:

Measure liquid formulas by volume when mixing, as bottle fill weights can vary

Similac® Special Care® 20 (SSC 20)
+
Similac® Special Care® 30 (SSC 30)
 
To Prepare:
Mix the Following:

 

23 Cal/fl oz

formula

 

2 parts SSC 20 + 1 part SSC 30

 

25 Cal/fl oz

formula

 

1 part SSC 20 + 1 part SSC 30

 

 

27 Cal/fl oz

formula*

 

 

1 part SSC 20 + 2 parts SSC 30

* EXAMPLE: To make 1 fl oz (approximately 30 mL) of 27-Cal formula, mix 10 mL of SSC 20 and 20 mL of SSC 30.

For convenience, use a Volu-Feed® bottle.

2 SSC 20 + 1 SSC 30 2 SSC 20 + 1 SSC 30
1 SSC 20 + 1 SSC 30 1 SSC 20 + 1 SSC 30
1 SSC 20 + 2 SSC 30 1 SSC 20 + 2 SSC 30
Similac® Special Care® 24 (SSC 24)
+
Similac® Special Care® 30 (SSC 30)
 
To Prepare:
Mix the Following:

 

26 Cal/fl oz

formula

 

2 parts SSC 24 + 1 part SSC 30

 

27 Cal/fl oz

formula

 

1 part SSC 24 + 1 part SSC 30

 

 

28 Cal/fl oz

formula

 

 

1 part SSC 24 + 2 parts SSC 30

† EXAMPLE: To make 1 fl oz (approximately 30 mL) of 28-Cal formula, mix 10 mL of SSC 24 and 20 mL of SSC 30.

For convenience, use a Volu-Feed bottle.

2 SSC 24 + 1 SSC 30 2 SSC 24 + 1 SSC 30
1 SSC 24 + 1 SSC 30 1 SSC 24 + 1 SSC 30
1 SSC 24 + 2 SSC 30 1 SSC 24 + 2 SSC 30

SIMILAC LIQUI-MIX SYSTEM MIXING GUIDE

Liquid Mix System graphic Liquid Mix System graphic
Similac Special Care 20 + Similac Special Care 24
Special Care 20 and Special Care 24 2 FL OZ ready to feed bottles Special Care 20 and Special Care 24 2 FL OZ ready to feed bottles
 

 
Nutrients
 
Per 100 Cal

 

Per 100 mL

 

Similac Special Care 20 (SSC 20)

 

1 part SSC 20 + 1 part SSC 24

 

Similac Special Care 24 (SSC 24)

 

Similac Special Care 20 (SSC 20)

 

1 part SSC 20 + 1 part SSC 24

 

Similac Special Care 24 (SSC 24)
Cal/fl oz
20
22
24
20
22
24

 

 

 

 

 

 

 

Energy, Cal

100

100

100

68

74

81

Volume, mL

148

134

124

100

100

100

Protein, g

3.00

3.00

3.00

2.03

2.23

2.43

Fat, g

5.43

5.43

5.43

3.67

4.04

4.41

Linoleic Acid, mg

700

700

700

473

521

568

Carbohydrate, g

10.3

10.3

10.3

7

7.7

8.4

Similac Special Care 20 + Similac® Special Care® 24 High Protein (3.3 g per 100 Cal)
Special Care 20 and Special Care 24 High Protein 2 FL OZ ready to feed bottles Special Care 20 and Special Care 24 High Protein 2 FL OZ ready to feed bottles
 

 

 

Nutrients
Per 100 Cal

 

Per 100 mL

 

Similac Special Care 20 (SSC 20)

 

1 part SSC 20 + 1 part SSC 24 HP

 

Similac Special Care 24 High Protein (SSC 24 HP)

 

Similac Special Care 20 (SSC 20)

 

1 part SSC 20 + 1 part SSC 24 HP

 

Similac Special Care 24 High Protein (SSC 24 HP)
Cal/fl oz
20
22
24
20
22
24

 

 

 

 

 

 

 

Energy, Cal

100

100

100

68

74

81

Volume, mL

148

134

124

100

100

100

Protein, g

3.0

3.16

3.3

2.03

2.35

2.68

Fat, g

5.43

5.43

5.43

3.67

4.04

4.4

Linoleic Acid, mg

700

700

700

473

521

568

Carbohydrate, g

10.3

10.15

10.0

7

7.5

8.1

Similac Special Care 20 + Similac Special Care 30
Special Care 20 and Special Care 30 2 FL OZ ready to feed bottles Special Care 20 and Special Care 30 2 FL OZ ready to feed bottles
 

 

 

Nutrients
Per 100 Cal

 

Per 100 mL

 

Similac Special Care 20 (SSC 20)

 

2 parts SSC 20 + 1 part SSC 30

 

1 part SSC 20 + 1 part SSC 30

 

1 part SSC 20 + 2 parts SSC 30

 

Similac Special Care 30 (SSC 30)

 

Similac Special Care 20 (SSC 20)

 

2 parts SSC 20 + 1 part SSC 30

 

1 part SSC 20 + 1 part SSC 30

 

1 part SSC 20 + 2 parts SSC 30

 

Similac Special Care 30 (SSC 30)
Cal/fl oz
20
23
25
27
30
20
23
25
27
30

 

 

 

 

 

 

 

 

 

 

 

Energy, Cal

100

100

100

100

100

68

79

85

90

101

Volume, mL

148

127

118

111

99

100

100

100

100

100

Protein, g

3.0

3.0

3.0

3.0

3.0

2.03

2.37

2.54

2.71

3.04

Fat, g

5.43

5.94

6.14

6.32

6.61

3.67

4.68

5.19

5.69

6.71

Linoleic Acid, mg

700

700

700

700

700

473

552

592

631

710

Carbohydrate, g

10.3

9.2

8.8

8.4

7.73

7

7.3

7.4

7.5

7.8

Similac Special Care 24 + Similac Special Care 30
Special Care 24 and Special Care 30 Special Care 24 and Special Care 30
 

 

 

Nutrients
Per 100 Cal

 

Per 100 mL

 

Similac Special Care 24 (SSC 24)

 

2 parts SSC 24 + 1 part SSC 30

 

1 part SSC 24 + 1 part SSC 30

 

1 part SSC 24 + 2 parts SSC 30

 

Similac Special Care 30 (SSC 30)

 

Similac Special Care 24 (SSC 24)

 

2 parts SSC 24 + 1 part SSC 30

 

1 part SSC 24 + 1 part SSC 30

 

1 part SSC 24 + 2 parts SSC 30

 

Similac Special Care 30 (SSC 30)
Cal/fl oz
24
26
27
28
30
24
26
27
28
30

 

 

 

 

 

 

 

 

 

 

 

Energy, Cal

100

100

100

100

100

81

88

91

95

101

Volume, mL

123

114

110

106

99

100

100

100

100

100

Protein, g

3.0

3.0

3.0

3.0

3.0

2.43

2.64

2.74

2.84

3.04

Fat, g

5.43

5.88

6.09

6.27

6.61

4.41

5.17

5.56

5.94

6.71

Linoleic Acid, mg

700

700

700

700

700

568

615

639

663

710

Carbohydrate, g

10.3

9.3

8.9

8.5

7.73

8.4

8.2

8.1

8.0

7.8

Similac Special Care 24 High Protein (3.3 g per 100 Cal) + Similac Special Care 30
Special Care 24 High Protein and Special Care 30 2 FL OZ ready to feed bottles Special Care 24 High Protein and Special Care 30 2 FL OZ ready to feed bottles
 
Nutrients
Per 100 Cal

 

Per 100 mL

 

Similac Special Care 24 HP (SSC 24 HP)

 

2 parts SSC 24 HP + 1 part SSC 30

 

1 part SSC 24 HP + 1 part SSC 30

 

1 part SSC 24 HP + 2 parts SSC 30

 

Similac Special Care 30 (SSC 30)

 

Similac Special Care 24 HP (SSC 24)

 

2 parts SSC 24 HP + 1 part SSC 30

 

1 part SSC 24 HP + 1 part SSC 30

 

1 part SSC 24 HP + 2 parts SSC 30

 

Similac Special Care 30 (SSC 30)
Cal/fl oz
24
26
27
28
30
24
26
27
28
30

 

 

 

 

 

 

 

 

 

 

 

Energy, Cal

100

100

100

100

100

81

88

91

95

101

Volume, mL

123

114

110

106

99

100

100

100

100

100

Protein, g

3.30

3.18

3.13

3.09

3.0

2.68

2.80

2.86

2.92

3.04

Fat, g

5.43

5.88

6.09

6.27

6.61

4.41

5.17

5.56

5.94

6.71

Linoleic Acid, mg

700

700

700

700

700

568

615

639

663

710

Carbohydrate, g

10.0

9.1

8.7

8.4

7.73

8.1

8.0

8.0

7.9

7.8

SIMILAC® HMF HP CL

The FIRST & ONLY nonacidified human milk fortifier with extensively hydrolyzed protein backed by 5 clinical studies.

When added to human milk, meets expert recommendations for protein1,2,* and other nutrients for the premature infant.1

SIMILAC HMF HP CL CAN BE USED WITH OUR SIMILAC® LIQUI-MIX® SYSTEM


Example Recipes for Similac HMF HP CL
 
Packets HP CL
 
Human Milk (mL)
 
Total Volume Fortified Human Milk
(standard mixing 1 pkt:25 mL)

1

25

30

2

50

60

4

100

120

8

200

240

16

400

480

* One packet mixed with 25 mL of human milk.

References: 1. Klein CJ. J Nutr. 2002;132(6, suppl 1):1395S-1577S. 2. Agostoni C, et al. J Pediatr Gastroenterol Nutr. 2010;58:85-91.

Human Milk Fortifier Hydrolyzed Protein concentrated liquid Human Milk Fortifier Hydrolyzed Protein concentrated liquid

Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid Recipes

Similac HMF HP CL Recipes
 
Packets HP CL
 
Human Milk (mL)
 
Total Volume Fortified Human Milk
(standard mixing 1 pkt:25 mL)

1

25

30

2

50

60

3

75

90

4

100

120

5

125

150

6

150

180

7

175

210

8

200

240

9

225

270

10

250

300

11

275

330

12

300

360

13

325

390

14

350

420

15

375

450

16

400

480

17

425

410

18

450

540

Not intended for feeding low-birth-weight infants after they reach a weight of 3600 g (approximately 8 lbs) or as directed by a physician.

SIMILAC HMF HP CL CAN BE USED WITH OUR SIMILAC LIQUI-MIX SYSTEM

OPTIMIZED PROTEIN FORTIFICATION

Liquid Protein Fortifier

use up to 72 hours after opening icon use up to 72 hours after opening icon
add human milk or infant formula add human milk or infant formula
Bottle icon Bottle icon
Use with human milk or formula

Designed to be mixed with donor milk, preterm milk, fortified milk, and formula

Digestion icon Digestion icon
Easy digestion and absorption

Extensively hydrolyzed protein for easy digestion and absorption

 

 
NUTRITIONAL CHARACTERISTICS OF LIQUID PROTEIN FORTIFIER
 

 

Protein: Source and Concentration –› 100% extensively hydrolyzed casein

16.7 g protein/100 mL; 1 g protein/6 mL

 

Calories –› 4 Cal/1 g protein

 

Osmolality –› 1 mL contributes ~12 mOsm/kg water when added to make

100 mL of the feeding

 

 Displacement –› 1 mL will displace 1 mL of feeding