Similac® Special Care® 20

Premature infant formula with iron

Similac® Special Care® 20

Premature infant formula with iron

A 20 Cal/fl oz., iron-fortified feeding for growing, low-birth-weight infants and premature infants.


  • OptiGROTM is our exclusive blend of DHA, Lutein, and Vitamin E; these important ingredients are found in breast milk
    • DHA for brain and eye development
    • Lutein to support eye health
    • Vitamin E, an important nutrient found in breast milk to support developing cells

Clinical Information

Nutritional Information

Unflavored Liquid - 100 Cal (5 fl oz)

Nutrient Data
Amount Per Serving
Calories 100
Volume, mL 148
Protein, g 3.0
Fat, g 5.43
Carbohydrate, g 10.3
Water, g 133
Linoleic Acid, mg 700
Potential Renal Solute Load, mOsm 27.8
Amount Per Serving
Vitamin A, IU 1250
Vitamin D, IU 150
Vitamin E, IU 4.0
Vitamin K, mcg 12
Thiamin (Vitamin B1), mcg 250
Riboflavin (Vitamin B2), mcg 620
Vitamin B6, mcg 250
Vitamin B12, mcg 0.55
Niacin, mcg 5000
Folic Acid (Folacin), mcg 37
Pantothenic Acid, mcg 1900
Biotin, mcg 37
Vitamin C (Ascorbic Acid), mg 37
Choline, mg 10
Inositol, mg 40
Amount Per Serving
Calcium, mg 180
Calcium, mEq 9.0
Phosphorus, mg 100
Magnesium, mg 12
Iron, mg 1.8
Zinc, mg 1.5
Manganese, mcg 12
Copper, mcg 250
Iodine, mcg 6
Selenium, mcg 2
Sodium, mg 43
Sodium, mEq 1.9
Potassium, mg 129
Potassium, mEq 3.3
Chloride, mg 81
Chloride, mEq 2.3

Unflavored Liquid - 1000 mL (1 L)

Nutrient Data
Amount Per Serving
Calories 676
Volume, mL 1000
Protein, g 20.29
Fat, g 36.72
Carbohydrate, g 69.7
Water, g 899
Linoleic Acid, mg 4734
Potential Renal Solute Load, mOsm 188.2
Amount Per Serving
Vitamin A, IU 8454
Vitamin D, IU 1014
Vitamin E, IU 27.1
Vitamin K, mcg 81.2
Thiamin (Vitamin B1), mcg 1691
Riboflavin (Vitamin B2), mcg 4193
Vitamin B6, mcg 1691
Vitamin B12, mcg 3.72
Niacin, mcg 33815
Folic Acid (Folacin), mcg 250
Pantothenic Acid, mcg 12850
Biotin, mcg 250
Vitamin C (Ascorbic Acid), mg 250
Choline, mg 68
Inositol, mg 271
Amount Per Serving
Calcium, mg 1217
Calcium, mEq 60.7
Phosphorus, mg 676
Magnesium, mg 81.2
Iron, mg 12.2
Zinc, mg 10.14
Manganese, mcg 81
Copper, mcg 1691
Iodine, mcg 41
Selenium, mcg 14
Sodium, mg 291
Sodium, mEq 12.6
Potassium, mg 872
Potassium, mEq 22.3
Chloride, mg 548
Chloride, mEq 15.5

Similac® Special Care® 20

OptiGRO™ is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk.

  • DHA for brain and eye development.
  • Lutein to support eye health.
  • Vitamin E, an important nutrient to support developing cells.
Lutein, a carotenoid naturally found in colostrum and human milk, has been shown to help support eye health in the preterm infant.1,2,3,4 Calcium: phosphorus content and ratio (1.8:1) supports intrauterine accretion rates.5 Approximately 2 mg iron/kg body weight per day when fed at 120 Cal/kg body weight per day. Gluten-free. Halal. Kosher.

  • 1 Canfield LM, et al. Eur J Nutr 2003;42:133-141.
  • 2 Schweigert FJ, et al. Eur J Nutr 2004;43:39-44.
  • 3 Patton S, et al. Lipids 1990;25:159-165.
  • 4 Rubin LP, et al. J Perinatol 2012;32:418-424.
  • 5 Mize et al. Am J Clin Nutr 1995;62:385-391.


Unflavored Liquid

Water, Nonfat Milk, Corn Syrup Solids, Medium chain Triglycerides, Lactose, Whey Protein Concentrate, Soy Oil, Coconut Oil. Less than 0.5% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Calcium Phosphate, Ascorbic Acid, Magnesium Chloride, Soy Lecithin, Monoglycerides, Potassium Citrate, m-Inositol, Carrageenan, Calcium Carbonate, Sodium Citrate, Potassium Hydroxide, Ferrous Sulfate, Choline Bitartrate, Taurine, Niacinamide, Choline Chloride, L-Carnitine, Zinc Sulfate, Potassium Chloride, Salt, Potassium Phosphate, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Riboflavin, Thiamine Chloride Hydrochloride, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Biotin, Phylloquinone, Sodium Selenate, Vitamin D3, Cyanocobalamin, and Nucleotides (Cytidine 5’-Monophosphate, Disodium Guanosine 5’-Monophosphate, Disodium Uridine 5’-Monophosphate, Adenosine 5’-Monophosphate).


Very-low-birthweight infants are particularly susceptible to gastrointestinal complications; therefore, feeding should be initiated cautiously.

Tolerance to enteral feedings should be confirmed by initially offering small volumes of formula followed by cautious progression to higher caloric feedings.

Spitting up, abdominal distension, abnormal stools or stool patterns, excessive gastric residuals, or other signs of intestinal dysfunction have been associated with enteral feeding before the intestinal tract is ready to accommodate the regimen. At first signs of these problems, enteral feeding should be slowed or discontinued.

Not intended for feeding low-birth-weight infants after they reach a weight of 3600 g (approximately 8 lb) or as directed by a physician.

Never use a microwave oven to warm formula. Serious burns can result.



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