Similac® Special Care® 24 High Protein

Premature high protein infant formula with iron

Similac® Special Care® 24 High Protein

Premature high protein infant formula with iron

A 24 Cal /fl oz., iron-fortified feeding for growing, low-birth-weight infants and premature infants who may need extra protein to help support growth.


  • OptiGROTM is our exclusive blend of DHA, Lutein, and Vitamin E; these important ingredients are found in breast milk
    • DHA for brain and eye development
    • Lutein to support eye health
    • Vitamin E, an important nutrient found in breast milk to support developing cells

Clinical Information

Nutritional Information

Unflavored Liquid - 100 Cal (4.2 fl oz)

Nutrient Data
Amount Per Serving
Calories 100
Volume, mL 123.22
Protein, g 3.3
Fat, g 5.43
Carbohydrate, g 10.0
Water, g 109
Linoleic Acid, mg 700
Potential Renal Solute Load, mOsm 29.5
Amount Per Serving
Vitamin A, IU 1250
Vitamin D, IU 150
Vitamin E, IU 4.0
Vitamin K, mcg 12
Thiamin (Vitamin B1), mcg 250
Riboflavin (Vitamin B2), mcg 620
Vitamin B6, mcg 250
Vitamin B12, mcg 0.55
Niacin, mcg 5000
Folic Acid (Folacin), mcg 37
Pantothenic Acid, mcg 1900
Biotin, mcg 37
Vitamin C (Ascorbic Acid), mg 37
Choline, mg 10
Inositol, mg 40
Amount Per Serving
Calcium, mg 180
Calcium, mEq 9.0
Phosphorus, mg 100
Magnesium, mg 12
Iron, mg 1.8
Zinc, mg 1.5
Manganese, mcg 12
Copper, mcg 250
Iodine, mcg 6
Selenium, mcg 2
Sodium, mg 43
Sodium, mEq 1.9
Potassium, mg 129
Potassium, mEq 3.3
Chloride, mg 81
Chloride, mEq 2.3

Unflavored Liquid - 1000 mL (1 L)

Nutrient Data
Amount Per Serving
Calories 812
Volume, mL 1000
Protein, g 26.8
Fat, g 44.07
Carbohydrate, g 81
Water, g 885
Linoleic Acid, mg 5681
Potential Renal Solute Load, mOsm 240
Amount Per Serving
Vitamin A, IU 10144
Vitamin D, IU 1217
Vitamin E, IU 32.5
Vitamin K, mcg 97.4
Thiamin (Vitamin B1), mcg 2029
Riboflavin (Vitamin B2), mcg 5032
Vitamin B6, mcg 2029
Vitamin B12, mcg 4.46
Niacin, mcg 40578
Folic Acid (Folacin), mcg 300
Pantothenic Acid, mcg 15419
Biotin, mcg 300
Vitamin C (Ascorbic Acid), mg 300
Choline, mg 81
Inositol, mg 325
Amount Per Serving
Calcium, mg 1461
Calcium, mEq 72.9
Phosphorus, mg 812
Magnesium, mg 97.4
Iron, mg 14.6
Zinc, mg 12.17
Manganese, mcg 97
Copper, mcg 2029
Iodine, mcg 49
Selenium, mcg 16
Sodium, mg 349
Sodium, mEq 15.2
Potassium, mg 1047
Potassium, mEq 26.8
Chloride, mg 657
Chloride, mEq 18.6

Similac® Special Care® 24 High Protein

OptiGRO™ is our exclusive blend of DHA, lutein and vitamin E: these important ingredients are found in breast milk.

  • DHA for brain and eye development.
  • Lutein to support eye health.
  • Vitamin E, an important nutrient to support developing cells.
3.3 g of protein/100 Cal, 10% more protein than Similac Special Care 24. Designed as a liquid option to meet the higher protein needs of very-low-birth-weight preterm infants. When fed at 120 Cal/kg/day, meets the recommended 4 g protein/kg/day for very-low-birth-weight infants.1,2,3,4 Lutein, a carotenoid naturally found in colostrum and human milk, has been shown to help support eye health in the preterm infant.5,6,7,8 Calcium: phosphorus content and ratio (1.8:1) supports intrauterine accretion rates.9 Approximately 2 mg iron/kg body weight per day when fed at 120 Cal/kg body weight per day. Gluten-free. Halal. Kosher.

  • 1 Ziegler EE. J Pediatr Gastroenterol Nutr 2007;45:170-174.
  • 2 Klein CJ. J Nutr 2002;132:1395S-1577S.
  • 3 Kleinman RE, Greer FR (eds): Pediatric Nutrition, 7th ed. Elk Grove Village, IL: American Academy of Pediatrics: 2014:93.
  • 4 Canadian Pediatric Society. CMAJ 1995;152(11):1765-1785.
  • 5 Canfield LM, et al. Eur J Nutr 2003;42:133-141.
  • 6 Schweigert FJ, et al. Eur J Nutr 2004;43:39-44.
  • 7 Patton S, et al. Lipids 1990;25:159-165.
  • 8 Rubin LP, et al. J Perinatol 2012;32:418-424.
  • 9 Mize et al. Am J Clin Nutr 1995;62:385-391.


Unflavored Liquid

Water, Nonfat Milk, Corn Syrup Solids, Medium chain Triglycerides, Whey Protein Concentrate, Lactose, Soy Oil, Coconut Oil. Less than 0.5% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Calcium Phosphate, Ascorbic Acid, Potassium Citrate, Calcium Carbonate, Soy Lecithin, Monoglycerides, Magnesium Chloride, m-Inositol, Sodium Citrate, Carrageenan, Potassium Hydroxide, Ferrous Sulfate, Choline Bitartrate, Taurine, Choline Chloride, Niacinamide, L-Carnitine, Zinc Sulfate, Potassium Chloride, Salt, Potassium Phosphate, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Riboflavin, Thiamine Chloride Hydrochloride, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Biotin, Phylloquinone, Sodium Selenate, Vitamin D3, Cyanocobalamin, and Nucleotides (Cytidine 5’-Monophosphate, Disodium Guanosine 5’-Monophosphate, Disodium Uridine 5’-Monophosphate, Adenosine 5’-Monophosphate).


Very-low-birthweight infants are particularly susceptible to gastrointestinal complications; therefore, feeding should be initiated cautiously.

Tolerance to enteral feedings should be confirmed by initially offering small volumes of formula followed by cautious progression to higher caloric feedings.

Spitting up, abdominal distension, abnormal stools or stool patterns, excessive gastric residuals, or other signs of intestinal dysfunction have been associated with enteral feeding before the intestinal tract is ready to accommodate the regimen. At first signs of these problems, enteral feeding should be slowed or discontinued.

Not intended for feeding low-birth-weight infants after they reach a weight of 3600 g (approximately 8 lb) or as directed by a physician.

Never use a microwave oven to warm formula. Serious burns can result.