Similac® Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid
Packaging Designed With Safety in Mind
The first & only nonacidified liquid human milk fortifier with extensively hydrolyzed protein
Backed by 5 clinical studies1-5
Clinically Demonstrated to Help Achieve Targeted Growth*
| Similac HMF HP CL† | Target Growth6,7 | |
| Weight Gain (g/kg/d) | ≥183-5 | >18 |
| Length Gain (cm/week) | >0.93,4 | >0.9 |
| Head Circumference Gain (cm/week) | >0.94 | >0.9 |
Studies Also Reported
TOLERANCE OUTCOMES 1,3
WEIGHT GAIN1–5,‡
PROTEIN STATUS (BUN LEVELS)3,4,§
METABOLIC ACIDOSIS1,3,5
Meet Your NICU Safety & Sterility Requirements
With Ready-To-Use, Single-Dose Packets
PACKETS FOR EASY NUTRIENT DELIVERY
SUPPORTS ASEPTIC HANDLING TO REDUCE RISK OF CONTAMINATION
COMMERCIALLY STERILE LIQUID
Meets the Academy of Nutrition and Dietetics and CDC recommendations to use liquid for NICU feedings
MINIMAL SUPPLIES NEEDED
Similac HMF HP CL Helps Meet The Following Expert Nutrient Intake Recommendations For Preterm Infants
Nutrients
| ESPGHAN Intake
| Koletzko et al
| Preterm Human Milk +
|
| Energy, Cal | 115-140 | 110-130 | 119 |
| Protein, g | 3.5-4.5|| | 3.5-4.5|| | 4.26 |
| Calcium, mg | 120-200 | 120-200 | 181 |
| Phosphorus, mg | 68-115 | 70-120 | 101 |
| Zinc, mg | 2-3 | 2-3 | 2 |
| Choline, mg | 8-55 | ≥33 | 16.2 |
| Sodium, mg | 69-115 | 69-115 | 69 |
| Potassium, mg | 90-179 | 79-195 | 152 |
| Chloride, mg | 106-177 | 105-177 | 134 |
A Comprehensive Portfolio of Preterm Nutrition Products
HMF Extensively Hydrolyzed Protein, Similac Special Care 24, Similac Special Care 30, and NeoSure are available through the Premature Nutrition Discharge Program.
Flexible, customizable feeding solutions, including Liquid Protein Fortifier for preterm infants in need of additional protein.
Supported by over 100 scientific publications
Used in more NICUs and hospitals than any other nutrition brand
Customizable, science-based options to meet patients
Over 50 years of Abbott research in preterm infant nutrition
Breast milk is the best feeding option for babies. HMF can be used when healthcare professional feels breast milk and/or donor milk are not sufficient. For complete product information, please reference the Pediatric Nutrition Product Guide or abbottnutrition.com.
* Mixed with human milk; the growth targets achieved varied among studies.
† Mixed with human milk.
‡ In the Schanler study, weight gain was improved SDAY1–SDAY15.
§ In clinically stable preterm infants with adequate renal function and hydration.
ǁ Wide range for preterm enteral protein intake.
¶ Base mixture of 25 mL preterm human milk + 5 mL SHMF HP CL, scaled up to 150 mL/kg/day.
# Abbott Infant Formula Survey Data on File, December 2024.
References: 1. Kumar N, et al. Am J Perinatol. 2017;34:1411-1416. 2. Clark B, et al. J Acad Nutr Diet. 2017;117(9 suppl 1):A11. 3. Schanler RJ, et al. J Pediatr. 2018;202:31-37. 4. Kim J, et al. J Pediatr Gastroenterol Nutr. 2015;61(6):665-671. 5. Lainwala S, et al. J Neonatal Perinatal Med. 2017;10(4):393-401. 6. Ehrenkranz RA, et al. Pediatrics. 2006;117:1253-1261. 7. Ehrenkranz RA, et al. Pediatrics. 1999; 104:280-289. 8. Embleton ND, et al. J Pediatr Gastroenterol Nutr. 2023;76(2):248-268. 9. Koletzko B, et al, eds. Nutritional Care of Preterm Infants. 2nd ed. Karger Medical and Scientific Publishers; 2021.
