* Mild to moderate dehydration.
Fever
Diarrhea or vomiting
Occasional morning sickness during a normal pregnancy
Heat
Consider increased fluid needs and importance of hydration during breastfeeding
SGLT1 is a protein found on the cell membrane of intestinal cells that moves sodium and glucose together across the small intestine.
Glucose is the nutrient in Pedialyte needed for active transport of sodium and water to occur.
The sodium gradient provides energy to push water into the bloodstream.
Because of the sodium-glucose cotransport, water is pushed into the bloodstream, leading to an increase in plasma volume.
Recent clinical trial data shows that Pedialyte increases plasma volume better than water.2,†
† Plasma volume expansion with Pedialyte over 2h was more than twice the expansion with water in a randomized, crossover study with 14 healthy adults.
References: 1. American Academy of Pediatrics Committee on Nutrition. Nutrition and Pediatric Diarrheal Disease. In: Greer FR, Abrams SA, eds. Pediatric Nutrition. 9th ed. American Academy of Pediatrics; 2025:807-844. 2. Williams JA, et al. Med Sci Sports Exerc. 55(9S):287, September 2023.
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